NOVELTIES
The Vertebrate Genome Annotation (VEGA) genome browser is a central repository for high quality manual annotation of vertebrate finished genome sequence. The majority of the annotation is from the HAVANA group at the Welcome Trust Sanger Institute. Registration not required.
Click here for more informationsPublished on 2012-03-02 12:12:28
LRG sequence format has been designed for the specific purpose of gene variant reporting. LRGs have fixed sequences that are independent of the genome so that they provide a stable framework for reporting variants. The data base provides a single-file record containing a uniquely stable reference DNA sequence along with all relevant transcript and protein sequences essential to the description of gene variants.
Click here for more informationsPublished on 2012-03-02 11:46:13
The HUGO Gene Nomenclature Committee (HGNC) has assigned unique gene symbols and names to over 33,000 human loci, of which around 19,000 are protein coding. http://genenames.org is a curated online repository of HGNC-approved gene nomenclature and associated resources including links to genomic, proteomic and phenotypic information, as well as dedicated gene family pages. Registration not required.
Click here for more informationsPublished on 2012-03-02 11:13:08
The Participant Portal is the single-entry point for interactions with the research and innovation programmes of the European Commission. It offers you the possibility to use a great variety of services and tools that facilitate the monitoring and the management of your proposals and projects throughout their lifecycle. Registration required.
Click here for more informationsPublished on 2012-03-02 10:12:08
ESF is a strong international network of 75 research funding, performing organisations and academics. ESF offers a number of opportunities, scientific and non-scientific, and provides career opportunities that could progress in management and administrative science activities. Registration required.
Click here for more informationsPublished on 2012-03-02 10:06:18
The UCSC Genome Browser is an on-line genome browser hosted by the University of California, Santa Cruz (UCSC).[2] [3] It is an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate species and major model organisms, integrated with a large collection of aligned annotations. Registration not required.
Click here for more informationsPublished on 2012-03-02 05:29:50
BindingDB is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of protein considered to be drug-targets with small, drug-like molecules. Registration not required.
Click here for more informationsPublished on 2012-02-29 12:12:49
The DIP database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions. Registration required.
Click here for more informationsPublished on 2012-02-29 12:01:55
PMP gives access to various models computed by comparative modeling methods provided by different partner sites, and provides access to various interactive services for model building, and quality assessment.Protein Model Portal is a component of the Nature PSI Structural Biology Knowledgebase Registration not required.
Click here for more informationsPublished on 2012-02-27 10:47:19
ExPASy is the Swiss Institute of Bioinformatics (SIB)Bioinformatics Resource Portal which provides access to scientific databases and software tools (i.e., resources) in different areas of life sciences including proteomics, genomics, phylogeny, systems biology, population genetics, transcriptomics etc. (see Categories in the left menu). On this portal you find resources from many different SIB groups as well as external institutions. Registration not required.
Click here for more informationsPublished on 2012-02-27 09:23:18
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Category: Gene information search, Gene expression
WashU Human Epigenome Browser allows: Epigenome
The browser currently hosts Human (and other species) Epigenome Atlas data produced by the Roadmap Epigenomics project,but lets users diverge from the strict genome-centric view of the UCSC browser to, for instance, view all genes (or promoters, or 3’ UTRs) in a given pathway side by side. “You can do lots of Google Maps-style operations, and you can look at your data in the context of their metadata.
Click here for more informationsPublished on 2012-02-27 09:21:04
Engine for Protein Similarity Search. SSearch is optimal for short peptides, GGsearch is optimal to find sequences similar (>80%) in length to the guery sequence, GLsearch is fine to match a short sequence or domain to the full protein. Registration not required.
Click here for more informationsPublished on 2012-02-27 09:10:36
The Connectivity Map uses computer algorithms and genome-wide expression data to explore the connection between diseases, genes, and drugs. Cmap is a collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules and simple pattern-matching algorithms that together enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes. The aim of theConnectivity Map project is to provide a systematic solution for the discovery of the type of functional connections between drugs, genes and diseases. Registration required.
Click here for more informationsPublished on 2012-02-24 10:27:50
The Diversity Outbred (DO) stock from JAX is a genetically diverse mouse resource and may be used as a tool for high resolution genetic mapping and validation of previously identified quantitative trait loci (QTLs) linked to disease susceptibility, drug resistance or behavioral phenotypes. It represents 45 million single nucleotide polymorphisms (SNPs) and 4 million copy number variations. Registration not required.
Click here for more informationsPublished on 2012-02-24 10:18:47
The International Knockout Mouse Consortium (IKMC) is a scientific endeavour to produce a collection of mouse lines, each lacking a protein-coding gene, using a combination of gene trapping and gene targeting in C57BL/6 mouse embryonic stem (ES) cells.(M Ringwald, Nucleic Acid Res 39, D849, 2011). Registration not required.
Click here for more informationsPublished on 2012-02-24 10:11:16
The IMPC envisages a ten year programme to undertake a broad-based, systematic genome-wide phenotyping project of knockout mice generated from the embryonic stem cell mutant resources developed by the International Knock-out Mouse Consortium (IKMC). It will produce knockout animals for each gene and analyze the phenotypic changes. Registration not required.
Click here for more informationsPublished on 2012-02-24 10:10:16
The open source ISA metadata tracking tools facilitates standards compliant collection, curation, local management and reuse of datasets in an increasingly diverse set of life science domains. Built around the ‘Investigation’ (the project context), ‘Study’ (a unit of research) and ‘Assay’ (analytical measurement) metadata categories, the tools are designed to manage studies employing one or a combination of technologies. Registration required.
Click here for more informationsPublished on 2012-02-13 06:00:00
The ISA Commons is a growing community that uses the ISA metadata tracking framework to facilitate standards-compliant collection, curation, management and reuse of datasets in an increasingly diverse set of life science domains Registration required.
Click here for more informationsPublished on 2012-02-13 05:57:29
HaploReg is a tool for exploring annotations of the noncoding genome at variants on haplotype blocks, such as candidate regulatory SNPs at disease-associated loci. It brings together data from chromatin-mapping and comparative-genomics studies. Researchers can enter common variants and see whether they fall in a highly conserved region, disrupt a regulatory motif or are associated with a regulatory element in a particular cell type. It provides the same information for common variants that tend to be inherited along with the ones entered. Registration not required.
Click here for more informationsPublished on 2012-02-12 12:13:34
RegulomeDB identifies binding sites and other elements in non-coding DNA.Use RegulomeDB to identify DNA features and regulatory elements in non-coding regions of the human genome by entering dbSNP IDs, Single nucleotides, a chromosomal region. Registration not required.
Click here for more informationsPublished on 2012-02-12 12:07:54
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